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» The Equivalence between Biology and Computation
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RECOMB
2006
Springer
16 years 1 months ago
Identifiability Issues in Phylogeny-Based Detection of Horizontal Gene Transfer
Prokaryotic organisms share genetic material across species boundaries by means of a process known as horizontal gene transfer (HGT). Detecting this process bears great significanc...
Cuong Than, Derek A. Ruths, Hideki Innan, Luay Nak...
RECOMB
2006
Springer
16 years 1 months ago
Efficient Enumeration of Phylogenetically Informative Substrings
We study the problem of enumerating substrings that are common amongst genomes that share evolutionary descent. For example, one might want to enumerate all identical (therefore co...
Stanislav Angelov, Boulos Harb, Sampath Kannan, Sa...
RECOMB
2010
Springer
15 years 8 months ago
The Clark Phase-able Sample Size Problem: Long-Range Phasing and Loss of Heterozygosity in GWAS
A phase transition is taking place today. The amount of data generated by genome resequencing technologies is so large that in some cases it is now less expensive to repeat the exp...
Bjarni V. Halldórsson, Derek Aguiar, Ryan T...
RECOMB
1999
Springer
15 years 5 months ago
Classifying proteins by family using the product of correlated p-values
An important goal in bioinformatics is determining the homology and function of proteins from their sequences. Pairwise sequence similarity algorithms are often employed for this ...
Timothy L. Bailey, William Noble Grundy
ISMB
1996
15 years 2 months ago
Gene Recognition in Cyanobacterium Genomic Sequence Data Using the Hidden Markov Model
We have developed a hidden Markov model (HMM)to detect the protein coding regions within one megabase contiguous sequence data, registered in a database called GenBankin eight ent...
Tetsushi Yada, Makoto Hirosawa