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» The Expressive Rate of Constraints
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WSC
2000
14 years 11 months ago
Mathematical programming models of discrete event system dynamics
Analytical models for the dynamics of some discrete event systems are introduced where the system trajectories are solutions to linear and mixed-integer programs. 1 BACKGROUND The...
Lee Schruben
BMCBI
2010
95views more  BMCBI 2010»
14 years 10 months ago
Modelling p-value distributions to improve theme-driven survival analysis of cancer transcriptome datasets
Background: Theme-driven cancer survival studies address whether the expression signature of genes related to a biological process can predict patient survival time. Although this...
Esteban Czwan, Benedikt Brors, David Kipling
89
Voted
BMCBI
2010
227views more  BMCBI 2010»
14 years 10 months ago
Accurate and efficient gp120 V3 loop structure based models for the determination of HIV-1 co-receptor usage
Background: HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-recepto...
Majid Masso, Iosif I. Vaisman
BMCBI
2007
105views more  BMCBI 2007»
14 years 10 months ago
Generating confidence intervals on biological networks
Background: In the analysis of networks we frequently require the statistical significance of some network statistic, such as measures of similarity for the properties of interact...
Thomas Thorne, Michael P. H. Stumpf
BMCBI
2007
99views more  BMCBI 2007»
14 years 10 months ago
Orthogonal projections to latent structures as a strategy for microarray data normalization
Background: During generation of microarray data, various forms of systematic biases are frequently introduced which limits accuracy and precision of the results. In order to prop...
Max Bylesjö, Daniel Eriksson, Andreas Sjö...