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ALMOB
2006
155views more  ALMOB 2006»
14 years 10 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
BMCBI
2006
152views more  BMCBI 2006»
14 years 10 months ago
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
Richard J. B. Dobson, Patricia B. Munroe, Mark J. ...
ESWA
2006
122views more  ESWA 2006»
14 years 10 months ago
Transmembrane segments prediction and understanding using support vector machine and decision tree
In recent years, there have been many studies focusing on improving the accuracy of prediction of transmembrane segments, and many significant results have been achieved. In spite...
Jieyue He, Hae-Jin Hu, Robert W. Harrison, Phang C...
NAR
2008
118views more  NAR 2008»
14 years 10 months ago
SuperTarget and Matador: resources for exploring drug-target relationships
The molecular basis of drug action is often not well understood. This is partly because the very abundant and diverse information generated in the past decades on drugs is hidden ...
Stefan Günther, Michael Kuhn 0004, Mathias Du...
BMCBI
2005
97views more  BMCBI 2005»
14 years 10 months ago
The yeast kinome displays scale free topology with functional hub clusters
Background: The availability of interaction databases provides an opportunity for researchers to utilize immense amounts of data exclusively in silico. Recently there has been an ...
Robin E. C. Lee, Lynn A. Megeney