Background: The number of sequenced eukaryotic genomes is rapidly increasing. This means that over time it will be hard to keep supplying customised gene finders for each genome. ...
Background: Chromatin immunoprecipitation combined with DNA microarrays (ChIP-chip) is an assay used for investigating DNA-protein-binding or post-translational chromatin/histone ...
The main goal of the motif finding problem is to detect novel, over-represented unknown signals in a set of sequences (e.g. transcription factor binding sites in a genome). The mo...
Chandan K. Reddy, Yao-Chung Weng, Hsiao-Dong Chian...
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Learning general functional dependencies is one of the main goals in machine learning. Recent progress in kernel-based methods has focused on designing flexible and powerful input...
Ioannis Tsochantaridis, Thomas Hofmann, Thorsten J...