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» The effect of sequence quality on sequence alignment
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BMCBI
2006
118views more  BMCBI 2006»
14 years 9 months ago
Automatic generation of gene finders for eukaryotic species
Background: The number of sequenced eukaryotic genomes is rapidly increasing. This means that over time it will be hard to keep supplying customised gene finders for each genome. ...
Kasper Munch, Anders Krogh
BMCBI
2010
153views more  BMCBI 2010»
14 years 9 months ago
Starr: Simple Tiling ARRay analysis of Affymetrix ChIP-chip data
Background: Chromatin immunoprecipitation combined with DNA microarrays (ChIP-chip) is an assay used for investigating DNA-protein-binding or post-translational chromatin/histone ...
Benedikt Zacher, Pei Fen Kuan, Achim Tresch
ALMOB
2006
155views more  ALMOB 2006»
14 years 9 months ago
Refining motifs by improving information content scores using neighborhood profile search
The main goal of the motif finding problem is to detect novel, over-represented unknown signals in a set of sequences (e.g. transcription factor binding sites in a genome). The mo...
Chandan K. Reddy, Yao-Chung Weng, Hsiao-Dong Chian...
BMCBI
2006
113views more  BMCBI 2006»
14 years 9 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
ICML
2004
IEEE
15 years 10 months ago
Support vector machine learning for interdependent and structured output spaces
Learning general functional dependencies is one of the main goals in machine learning. Recent progress in kernel-based methods has focused on designing flexible and powerful input...
Ioannis Tsochantaridis, Thomas Hofmann, Thorsten J...