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BMCBI
2007
95views more  BMCBI 2007»
14 years 10 months ago
Phylogenetic tree information aids supervised learning for predicting protein-protein interaction based on distance matrices
Background: Protein-protein interactions are critical for cellular functions. Recently developed computational approaches for predicting protein-protein interactions utilize co-ev...
Roger A. Craig, Li Liao
BMCBI
2008
178views more  BMCBI 2008»
14 years 10 months ago
A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic ana
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
Bin Liu, Xiaolong Wang, Lei Lin, Qiwen Dong, Xuan ...
BMCBI
2006
146views more  BMCBI 2006»
14 years 10 months ago
Recursive gene selection based on maximum margin criterion: a comparison with SVM-RFE
Background: In class prediction problems using microarray data, gene selection is essential to improve the prediction accuracy and to identify potential marker genes for a disease...
Satoshi Niijima, Satoru Kuhara
BMCBI
2005
117views more  BMCBI 2005»
14 years 10 months ago
An SVM-based system for predicting protein subnuclear localizations
Background: The large gap between the number of protein sequences in databases and the number of functionally characterized proteins calls for the development of a fast computatio...
Zhengdeng Lei, Yang Dai
VLSISP
2010
254views more  VLSISP 2010»
14 years 8 months ago
Manifold Based Local Classifiers: Linear and Nonlinear Approaches
Abstract In case of insufficient data samples in highdimensional classification problems, sparse scatters of samples tend to have many ‘holes’—regions that have few or no nea...
Hakan Cevikalp, Diane Larlus, Marian Neamtu, Bill ...