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83
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BMCBI
2010
156views more  BMCBI 2010»
14 years 10 months ago
Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
James H. Bullard, Elizabeth Purdom, Kasper D. Hans...
123
Voted
BMCBI
2011
14 years 5 months ago
Statistical Test of Expression Pattern (STEPath): a new strategy to integrate gene expression data with genomic information in i
Background: In the last decades, microarray technology has spread, leading to a dramatic increase of publicly available datasets. The first statistical tools developed were focuse...
Paolo G. V. Martini, Davide Risso, Gabriele Sales,...
107
Voted
BMCBI
2008
162views more  BMCBI 2008»
14 years 10 months ago
Improved identification of conserved cassette exons using Bayesian networks
Background: Alternative splicing is a major contributor to the diversity of eukaryotic transcriptomes and proteomes. Currently, large scale detection of alternative splicing using...
Rileen Sinha, Michael Hiller, Rainer Pudimat, Ulri...
88
Voted
BMCBI
2007
117views more  BMCBI 2007»
14 years 10 months ago
Meta-analysis of several gene lists for distinct types of cancer: A simple way to reveal common prognostic markers
Background: Although prognostic biomarkers specific for particular cancers have been discovered, microarray analysis of gene expression profiles, supported by integrative analysis...
Xinan Yang, Xiao Sun
82
Voted
NAR
2007
155views more  NAR 2007»
14 years 9 months ago
AthaMap web tools for the analysis and identification of co-regulated genes
The AthaMap database generates a map of cisregulatory elements for the whole Arabidopsis thaliana genome. This database has been extended by new tools to identify common cis-regul...
Claudia Galuschka, Martin Schindler, Lorenz Bü...