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BMCBI
2004
90views more  BMCBI 2004»
15 years 4 months ago
Statistical monitoring of weak spots for improvement of normalization and ratio estimates in microarrays
Background: Several aspects of microarray data analysis are dependent on identification of genes expressed at or near the limits of detection. For example, regression-based normal...
Igor Dozmorov, Nicholas Knowlton, Yuhong Tang, Mic...
BMCBI
2004
196views more  BMCBI 2004»
15 years 4 months ago
MUSCLE: a multiple sequence alignment method with reduced time and space complexity
Background: In a previous paper, we introduced MUSCLE, a new program for creating multiple alignments of protein sequences, giving a brief summary of the algorithm and showing MUS...
Robert C. Edgar
BMCBI
2004
101views more  BMCBI 2004»
15 years 4 months ago
A database for G proteins and their interaction with GPCRs
Background: G protein-coupled receptors (GPCRs) transduce signals from extracellular space into the cell, through their interaction with G proteins, which act as switches forming ...
Antigoni L. Elefsinioti, Pantelis G. Bagos, Ioanni...
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BMCBI
2004
174views more  BMCBI 2004»
15 years 4 months ago
Implications for domain fusion protein-protein interactions based on structural information
Background: Several in silico methods exist that were developed to predict protein interactions from the copious amount of genomic and proteomic data. One of these methods is Doma...
Jer-Ming Chia, Prasanna R. Kolatkar
BMCBI
2004
190views more  BMCBI 2004»
15 years 4 months ago
RAG: RNA-As-Graphs web resource
Background: The proliferation of structural and functional studies of RNA has revealed an increasing range of RNA's structural repertoire. Toward the objective of systematic ...
Daniela Fera, Namhee Kim, Nahum Shiffeldrim, Julie...
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