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BMCBI
2006
101views more  BMCBI 2006»
13 years 6 months ago
SynTReN: a generator of synthetic gene expression data for design and analysis of structure learning algorithms
Background: The development of algorithms to infer the structure of gene regulatory networks based on expression data is an important subject in bioinformatics research. Validatio...
Tim Van den Bulcke, Koen Van Leemput, Bart Naudts,...
BMCBI
2010
164views more  BMCBI 2010»
13 years 6 months ago
Investigating the validity of current network analysis on static conglomerate networks by protein network stratification
Background: A molecular network perspective forms the foundation of systems biology. A common practice in analyzing protein-protein interaction (PPI) networks is to perform networ...
Minlu Zhang, Long J. Lu
AIME
2005
Springer
13 years 8 months ago
An Algorithm to Learn Causal Relations Between Genes from Steady State Data: Simulation and Its Application to Melanoma Dataset
In recent years, a few researchers have challenged past dogma and suggested methods (such as the IC algorithm) for inferring causal relationship among variables using steady state ...
Xin Zhang, Chitta Baral, Seungchan Kim
COLT
1995
Springer
13 years 9 months ago
Regression NSS: An Alternative to Cross Validation
The Noise Sensitivity Signature (NSS), originally introduced by Grossman and Lapedes (1993), was proposed as an alternative to cross validation for selecting network complexity. I...
Michael P. Perrone, Brian S. Blais
BMCBI
2007
136views more  BMCBI 2007»
13 years 6 months ago
Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
Xiaoyu Chen, Mathieu Blanchette