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» Variability Models Must Not be Invariant!
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ALMOB
2006
80views more  ALMOB 2006»
14 years 9 months ago
Pattern statistics on Markov chains and sensitivity to parameter estimation
Background: In order to compute pattern statistics in computational biology a Markov model is commonly used to take into account the sequence composition. Usually its parameter mu...
Grégory Nuel
BMCBI
2010
137views more  BMCBI 2010»
14 years 9 months ago
Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments
Background: While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor ...
Michael L. Sierk, Michael E. Smoot, Ellen J. Bass,...
GPCE
2004
Springer
15 years 2 months ago
Taming Macros
Scheme includes a simple yet powerful macro mechanism. Using macros, programmers can easily extend the language with new kinds of expressions and definitions, thus abstracting ove...
Ryan Culpepper, Matthias Felleisen
CORR
2010
Springer
103views Education» more  CORR 2010»
14 years 8 months ago
BioBlender: a Software for Intuitive Representation of Surface Properties of Biomolecules
In this and the associated article BioBlender: A Software for Intuitive Representation of Surface Properties of Biomolecules [1], we present BioBlender as a complete instrument fo...
Raluca Mihaela Andrei, Marco Callieri, Maria Franc...
75
Voted
BMCBI
2005
124views more  BMCBI 2005»
14 years 9 months ago
Evaluating concentration estimation errors in ELISA microarray experiments
Background: Enzyme-linked immunosorbent assay (ELISA) is a standard immunoassay to estimate a protein's concentration in a sample. Deploying ELISA in a microarray format perm...
Don Simone Daly, Amanda M. White, Susan M. Varnum,...