Background: Predicting the suppression activity of antisense oligonucleotide sequences is the main goal of the rational design of nucleic acids. To create an effective predictive ...
Replication and caching mechanisms are often employed to enhance the performance of Web applications. In this article, we present a qualitative and quantitative analysis of state-...
Background: In a previous report (La et al., Proteins, 2005), we have demonstrated that the identification of phylogenetic motifs, protein sequence fragments conserving the overal...
Model-Driven Engineering (MDE) advocates the use of models at every step of the software development process. Within this context, a team of engineers collectively and collaborati...
In this paper we show how common speech recognition training criteria such as the Minimum Phone Error criterion or the Maximum Mutual Information criterion can be extended to inco...