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96
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BMCBI
2007
15 years 20 days ago
2007
Background: Transcription factors (TFs) are key regulatory proteins that enhance or repress the transcriptional rate of their target genes by binding to specific promoter regions ...
119
Voted
NAR
2006
15 years 18 days ago
2006
Recent work has demonstrated that microRNAs (miRNAs) are involved in critical biological processes by suppressing the translation of coding genes. This work develops an integrated...
BMCBI
2005
15 years 17 days ago
2005
Background: Public databases now contain multitude of complete bacterial genomes, including several genomes of the same species. The available data offers new opportunities to add...
118
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BMCBI
2005
15 years 17 days ago
2005
Background: The identification of local similarities between two protein structures can provide clues of a common function. Many different methods exist for searching for similar ...
113
Voted
BMCBI
2004
15 years 16 days ago
2004
Background: G protein-coupled receptors (GPCRs) transduce signals from extracellular space into the cell, through their interaction with G proteins, which act as switches forming ...