Motivation: Extracting functional information from protein–protein interactions (PPI) poses significant challenges arising from the noisy, incomplete, generic and static nature...
Background: False occurrences of functional motifs in protein sequences can be considered as random events due solely to the sequence composition of a proteome. Here we use a nume...
Background: The sparse connectivity of protein-protein interaction data sets makes identification of functional modules challenging. The purpose of this study is to critically eva...
Background: The functional annotation of proteins relies on published information concerning their close and remote homologues in sequence databases. Evidence for remote sequence ...
Charles Richard Bradshaw, Vineeth Surendranath, Bi...
Background: S. cerevisiae, A. thaliana and M. musculus are well-studied organisms in biology and the sequencing of their genomes was completed many years ago. It is still a challe...
Leander Schietgat, Celine Vens, Jan Struyf, Hendri...