Allostery is the most direct, rapid and efficient way of regulating protein function, ranging from the control of metabolic mechanisms to signaltransduction pathways. However, an ...
Zhimin Huang, Liang Zhu, Yan Cao, Geng Wu, Xinyi L...
1 Profile Hidden Markov Models (profile HMMs) are used as a popular bioinformatics tool for sensitive database searching, e.g. a set of not annotated protein sequences is compared...
The coiled-coil protein domain is a widespread structural motif known to be involved in a wealth of key interactions in cells and organisms. Coiled-coil recognition and prediction ...
Abstract. A clustering method is presented which can be applied to semantically annotated resources in the context of ontological knowledge bases. This method can be used to discov...
We present an overview of the Jahob system for modular analysis of data structure properties. Jahob uses a subset of Java as the implementation language and annotations with formu...