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BIBM
2008
IEEE
111views Bioinformatics» more  BIBM 2008»
15 years 6 months ago
Estimating Regulatory Associations of Genomic Loci and Biological Pathways in Lymphoblastoid Cells
Genetical genomics has been established to study genetic variation of gene expression. It treats transcript expression as a quantitative trait and identifies putative regulatory l...
Jung Hoon Woo, Eunjee Lee, Sung-Bum Cho, Ju Han Ki...
BIBM
2008
IEEE
142views Bioinformatics» more  BIBM 2008»
15 years 6 months ago
Using Global Sequence Similarity to Enhance Biological Sequence Labeling
Identifying functionally important sites from biological sequences, formulated as a biological sequence labeling problem, has broad applications ranging from rational drug design ...
Cornelia Caragea, Jivko Sinapov, Drena Dobbs, Vasa...
BIBM
2008
IEEE
141views Bioinformatics» more  BIBM 2008»
15 years 6 months ago
Protein-Protein Interaction Network Alignment by Quantitative Simulation
We adapt a network simulation algorithm called quantitative simulation (QSim) for use in the alignment of biological networks. Unlike most network alignment methods, QSim finds l...
Perry Evans, Ted Sandler, Lyle H. Ungar
BIRD
2008
Springer
15 years 1 months ago
Efficient Seeding Techniques for Protein Similarity Search
Abstract. We apply the concept of subset seeds proposed in [1] to similarity search in protein sequences. The main question studied is the design of efficient seed alphabets to con...
Mikhail A. Roytberg, Anna Gambin, Laurent No&eacut...
BIRD
2008
Springer
15 years 1 months ago
Translational Control by RNA-RNA Interaction: Improved Computation of RNA-RNA Binding Thermodynamics
The thermodynamics of RNA-RNA interaction consists of two components: the energy necessary to make a potential binding region accessible, i.e., unpaired, and the energy gained from...
Ulrike Mückstein, Hakim Tafer, Stephan H. F. ...