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BMCBI
2006
126views more  BMCBI 2006»
14 years 10 months ago
A minimally invasive multiple marker approach allows highly efficient detection of meningioma tumors
Background: The development of effective frameworks that permit an accurate diagnosis of tumors, especially in their early stages, remains a grand challenge in the field of bioinf...
Andreas Keller, Nicole Ludwig, Nicole Comtesse, An...
BMCBI
2006
122views more  BMCBI 2006»
14 years 10 months ago
A comparison of univariate and multivariate gene selection techniques for classification of cancer datasets
Background: Gene selection is an important step when building predictors of disease state based on gene expression data. Gene selection generally improves performance and identifi...
Carmen Lai, Marcel J. T. Reinders, Laura J. van't ...
82
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BMCBI
2006
105views more  BMCBI 2006»
14 years 10 months ago
Integrative investigation of metabolic and transcriptomic data
Background: New analysis methods are being developed to integrate data from transcriptome, proteome, interactome, metabolome, and other investigative approaches. At the same time,...
Pinar Pir, Betül Kirdar, Andrew Hayes, Z. Ils...
BMCBI
2006
97views more  BMCBI 2006»
14 years 10 months ago
PDA: Pooled DNA analyzer
Background: Association mapping using abundant single nucleotide polymorphisms is a powerful tool for identifying disease susceptibility genes for complex traits and exploring pos...
Hsin-Chou Yang, Chia-Ching Pan, Chin-Yu Lin, Cathy...
BMCBI
2006
108views more  BMCBI 2006»
14 years 10 months ago
NOXclass: prediction of protein-protein interaction types
Background: Structural models determined by X-ray crystallography play a central role in understanding protein-protein interactions at the molecular level. Interpretation of these...
Hongbo Zhu, Francisco S. Domingues, Ingolf Sommer,...