Background: The development of effective frameworks that permit an accurate diagnosis of tumors, especially in their early stages, remains a grand challenge in the field of bioinf...
Andreas Keller, Nicole Ludwig, Nicole Comtesse, An...
Background: Gene selection is an important step when building predictors of disease state based on gene expression data. Gene selection generally improves performance and identifi...
Carmen Lai, Marcel J. T. Reinders, Laura J. van't ...
Background: New analysis methods are being developed to integrate data from transcriptome, proteome, interactome, metabolome, and other investigative approaches. At the same time,...
Background: Association mapping using abundant single nucleotide polymorphisms is a powerful tool for identifying disease susceptibility genes for complex traits and exploring pos...
Background: Structural models determined by X-ray crystallography play a central role in understanding protein-protein interactions at the molecular level. Interpretation of these...
Hongbo Zhu, Francisco S. Domingues, Ingolf Sommer,...