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BIOINFORMATICS
2011
14 years 7 months ago
All-atom knowledge-based potential for RNA structure prediction and assessment
Motivation: Over the recent years, the vision that RNA simply serves as information transfer molecule has dramatically changed. The study of the sequence/structure/function relati...
Emidio Capriotti, Tomás Norambuena, Marc A....
120
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BMCBI
2011
14 years 7 months ago
SNP-based pathway enrichment analysis for genome-wide association studies
Background: Recently we have witnessed a surge of interest in using genome-wide association studies (GWAS) to discover the genetic basis of complex diseases. Many genetic variatio...
Lingjie Weng, Fabio Macciardi, Aravind Subramanian...
BMCBI
2011
14 years 7 months ago
The PathOlogist: An Automated Tool for Pathway-Centric Analysis
Background: The PathOlogist is a new tool designed to transform large sets of gene expression data into quantitative descriptors of pathway-level behavior. The tool aims to provid...
Sharon I. Greenblum, Sol Efroni, Carl F. Schaefer,...
BMCBI
2011
14 years 7 months ago
Phenotype Recognition with Combined Features and Random Subspace Classifier Ensemble
Background: Automated, image based high-content screening is a fundamental tool for discovery in biological science. Modern robotic fluorescence microscopes are able to capture th...
Bailing Zhang, Tuan D. Pham
197
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MICROMACHINES
2011
14 years 7 months ago
Modeling Self-Assembly Across Scales: The Unifying Perspective of Smart Minimal Particles
: A wealth of current research in microengineering aims at fabricating devices of increasing complexity, notably by (self-)assembling elementary components into heterogeneous funct...
Massimo Mastrangeli, Grégory Mermoud, Alche...