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BIOINFORMATICS
2011
15 years 17 days ago
All-atom knowledge-based potential for RNA structure prediction and assessment
Motivation: Over the recent years, the vision that RNA simply serves as information transfer molecule has dramatically changed. The study of the sequence/structure/function relati...
Emidio Capriotti, Tomás Norambuena, Marc A....
BMCBI
2011
15 years 17 days ago
SNP-based pathway enrichment analysis for genome-wide association studies
Background: Recently we have witnessed a surge of interest in using genome-wide association studies (GWAS) to discover the genetic basis of complex diseases. Many genetic variatio...
Lingjie Weng, Fabio Macciardi, Aravind Subramanian...
BMCBI
2011
15 years 17 days ago
The PathOlogist: An Automated Tool for Pathway-Centric Analysis
Background: The PathOlogist is a new tool designed to transform large sets of gene expression data into quantitative descriptors of pathway-level behavior. The tool aims to provid...
Sharon I. Greenblum, Sol Efroni, Carl F. Schaefer,...
BMCBI
2011
15 years 17 days ago
Phenotype Recognition with Combined Features and Random Subspace Classifier Ensemble
Background: Automated, image based high-content screening is a fundamental tool for discovery in biological science. Modern robotic fluorescence microscopes are able to capture th...
Bailing Zhang, Tuan D. Pham
MICROMACHINES
2011
15 years 16 days ago
Modeling Self-Assembly Across Scales: The Unifying Perspective of Smart Minimal Particles
: A wealth of current research in microengineering aims at fabricating devices of increasing complexity, notably by (self-)assembling elementary components into heterogeneous funct...
Massimo Mastrangeli, Grégory Mermoud, Alche...