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CSB
2005
IEEE
137views Bioinformatics» more  CSB 2005»
15 years 3 months ago
A Learned Comparative Expression Measure for Affymetrix GeneChip DNA Microarrays
Perhaps the most common question that a microarray study can ask is, “Between two given biological conditions, which genes exhibit changed expression levels?” Existing methods...
Will Sheffler, Eli Upfal, John Sedivy, William Sta...
127
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BMCBI
2005
201views more  BMCBI 2005»
14 years 9 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
WABI
2005
Springer
110views Bioinformatics» more  WABI 2005»
15 years 2 months ago
Alignment of Tandem Repeats with Excision, Duplication, Substitution and Indels (EDSI)
Abstract. Traditional sequence comparison by alignment applies a mutation model comprising two events, substitutions and indels (insertions or deletions) of single positions (SI). ...
Michael Sammeth, Thomas Weniger, Dag Harmsen, Jens...
BMCBI
2005
63views more  BMCBI 2005»
14 years 9 months ago
Individual sequences in large sets of gene sequences may be distinguished efficiently by combinations of shared sub-sequences
Background: Most current DNA diagnostic tests for identifying organisms use specific oligonucleotide probes that are complementary in sequence to, and hence only hybridise with th...
Mark J. Gibbs, John S. Armstrong, Adrian J. Gibbs
GECCO
2005
Springer
136views Optimization» more  GECCO 2005»
15 years 3 months ago
Evolutionary computation and the c-value paradox
The C-value Paradox is the name given in biology to the wide variance in and often very large amount of DNA in eukaryotic genomes and the poor correlation between DNA length and p...
Sean Luke