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BMCBI
2006
14 years 10 months ago
2006
Background: Multiple sequence alignment is the foundation of many important applications in bioinformatics that aim at detecting functionally important regions, predicting protein...
BMCBI
2006
14 years 10 months ago
2006
Background: Genome databases contain diverse kinds of information, including gene annotations and nucleotide and amino acid sequences. It is not easy to integrate such information...
BMCBI
2006
14 years 10 months ago
2006
Background: The most fundamental task using gene expression data in clinical oncology is to classify tissue samples according to their gene expression levels. Compared with tradit...
BMCBI
2006
14 years 10 months ago
2006
Background: Molecular maps have been developed for many species, and are of particular importance for varietal development and comparative genomics. However, despite the existence...
BMCBI
2006
2006
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
14 years 10 months ago
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...