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BMCBI
2005
138views more  BMCBI 2005»
15 years 5 months ago
Detailed protein sequence alignment based on Spectral Similarity Score (SSS)
Background: The chemical property and biological function of a protein is a direct consequence of its primary structure. Several algorithms have been developed which determine ali...
Kshitiz Gupta, Dina Thomas, S. V. Vidya, K. V. Ven...
BMCBI
2005
113views more  BMCBI 2005»
15 years 5 months ago
PentaPlot: A software tool for the illustration of genome mosaicism
Background: Dekapentagonal maps depict the phylogenetic relationships of five genomes in a visually appealing diagram and can be viewed as an alternative to a single evolutionary ...
Lutz Hamel, Olga Zhaxybayeva, J. Peter Gogarten
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BMCBI
2005
112views more  BMCBI 2005»
15 years 5 months ago
Visualization methods for statistical analysis of microarray clusters
Background: The most common method of identifying groups of functionally related genes in microarray data is to apply a clustering algorithm. However, it is impossible to determin...
Matthew A. Hibbs, Nathaniel C. Dirksen, Kai Li, Ol...
BMCBI
2005
126views more  BMCBI 2005»
15 years 5 months ago
Integrative analysis of multiple gene expression profiles with quality-adjusted effect size models
Background: With the explosion of microarray studies, an enormous amount of data is being produced. Systematic integration of gene expression data from different sources increases...
Pingzhao Hu, Celia M. T. Greenwood, Joseph Beyene
BMCBI
2005
102views more  BMCBI 2005»
15 years 5 months ago
Genome-wide identification of the regulatory targets of a transcription factor using biochemical characterization and computatio
Background: A major challenge in computational genomics is the development of methodologies that allow accurate genome-wide prediction of the regulatory targets of a transcription...
Emmitt R. Jolly, Chen-Shan Chin, Ira Herskowitz, H...
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