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195
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BMCBI
2005
15 years 5 months ago
2005
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
174
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BMCBI
2005
15 years 5 months ago
2005
Background: Two central problems in computational biology are the determination of the alignment and phylogeny of a set of biological sequences. The traditional approach to this p...
149
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BMCBI
2005
15 years 5 months ago
2005
Background: The recent explosion in the availability of complete genome sequences has led to the cataloging of tens of thousands of new proteins and putative proteins. Many of the...
143
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BMCBI
2005
15 years 5 months ago
2005
Background: Type 1 diabetes mellitus (T1DM) is a autoimmune disease caused by a long-term negative balance between immune-mediated beta-cell damage and beta-cell repair/regenerati...
148
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BMCBI
2005
15 years 5 months ago
2005
Background: Protein sequence alignments have become indispensable for virtually any evolutionary, structural or functional study involving proteins. Modern sequence search and com...