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JCB
2000
103views more  JCB 2000»
14 years 10 months ago
Testing for Differentially-Expressed Genes by Maximum-Likelihood Analysis of Microarray Data
Although two-color uorescent DNA microarrays are now standard equipment in many molecular biology laboratories, methods for identifying differentially expressed genes in microarra...
Trey Ideker, Vesteinn Thorsson, Andrew F. Siegel, ...
JCB
2000
146views more  JCB 2000»
14 years 10 months ago
Bayesian Segmentation of Protein Secondary Structure
We present a novel method for predicting the secondary structure of a protein from its amino acid sequence. Most existing methods predict each position in turn based on a local wi...
Scott C. Schmidler, Jun S. Liu, Douglas L. Brutlag
JCNS
2000
73views more  JCNS 2000»
14 years 10 months ago
Models of Calmodulin Trapping and CaM Kinase II Activation in a Dendritic Spine
Activation of calcium/calmodulin-dependent protein kinase II (CaMKII) by calmodulin following calcium entry into the cell is important for long-term potentiation (LTP). Here a mode...
William Holmes
JCNS
2000
126views more  JCNS 2000»
14 years 10 months ago
Alpha-Frequency Rhythms Desynchronize over Long Cortical Distances: A Modeling Study
Neocortical networks of excitatory and inhibitory neurons can display alpha()-frequency rhythms when an animal is in a resting or unfocused state. Unlike some - and -frequency rhy...
Stephanie R. Jones, David J. Pinto, Tasso J. Kaper...
JCNS
2000
120views more  JCNS 2000»
14 years 10 months ago
Robust Spectrotemporal Reverse Correlation for the Auditory System: Optimizing Stimulus Design
Abstract. The spectrotemporal receptive field (STRF) is a functional descriptor of the linear processing of timevarying acoustic spectra by the auditory system. By cross-correlatin...
David J. Klein, Didier A. Depireux, Jonathan Z. Si...
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