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JCB
1998
84views more  JCB 1998»
14 years 11 months ago
Methods and Statistics for Combining Motif Match Scores
Position-speci c scoring matrices are useful for representing and searching for protein sequence motifs. A sequence family can often be described by a group of one or more motifs,...
Timothy L. Bailey, Michael Gribskov
JCB
2008
111views more  JCB 2008»
14 years 11 months ago
Sorting Genomes with Centromeres by Translocations
A centromere is a special region in the chromosome that plays a vital role during cell division. Every new chromosome created by a genome rearrangement event must have a centromer...
Michal Ozery-Flato, Ron Shamir
JCB
2006
126views more  JCB 2006»
15 years 18 hour ago
Combinatorics of Saturated Secondary Structures of RNA
Following Zuker (1986), a saturated secondary structure for a given RNA sequence is a secondary structure such that no base pair can be added without violating the definition of s...
P. Clote
JCB
2006
79views more  JCB 2006»
15 years 18 hour ago
A Stability Boundary Based Method for Finding Saddle Points on Potential Energy Surfaces
The task of finding saddle points on potential energy surfaces plays a crucial role in understanding the dynamics of a micromolecule as well as in studying the folding pathways of...
Chandan K. Reddy, Hsiao-Dong Chiang
JCB
2000
101views more  JCB 2000»
14 years 12 months ago
Evaluation Measures of Multiple Sequence Alignments
Multiple sequence alignments (MSAs) are frequently used in the study of families of protein sequences or DNA/RNA sequences. They are a fundamental tool for the understanding of th...
Gaston H. Gonnet, Chantal Korostensky, Steven A. B...