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BMCBI
2005
14 years 11 months ago
2005
Background: Multiple genome alignment is an important problem in bioinformatics. An important subproblem used by many multiple alignment approaches is that of aligning two multipl...
BMCBI
2005
14 years 11 months ago
2005
Background: Protein sequence motifs are by definition short fragments of conserved amino acids, often associated with a specific function. Accordingly protein sequence profiles de...
114
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BMCBI
2005
14 years 11 months ago
2005
Background: The evaluation of statistical significance has become a critical process in identifying differentially expressed genes in microarray studies. Classical p-value adjustm...
107
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BMCBI
2005
14 years 11 months ago
2005
Background: A major challenge in computational genomics is the development of methodologies that allow accurate genome-wide prediction of the regulatory targets of a transcription...
BMCBI
2005
14 years 11 months ago
2005
Background: With the exponential increase in genomic sequence data there is a need to develop automated approaches to deducing the biological functions of novel sequences with hig...