BMCBI
2008
14 years 9 months ago
2008
Background: The import of most intraperoxisomal proteins is mediated by peroxisome targeting signals at their C-termini (PTS1) or N-terminal regions (PTS2). Both signals have been...
BMCBI
2008
14 years 9 months ago
2008
Background: Historically, two categories of computational algorithms (alignment-based and alignment-free) have been applied to sequence comparison
BMCBI
2008
14 years 9 months ago
2008
69
Voted
BMCBI
2008
14 years 9 months ago
2008
Background: Ionic current blockade signal processing, for use in nanopore detection, offers a promising new way to analyze single molecule properties with potential implications f...
BMCBI
2008
14 years 9 months ago
2008
teps. First, we abstracted protein interactions onto orthologous cluster links. For a given source interaction, if both proteins belonged to a cluster, we constructed a link betwee...
BMCBI
2008
14 years 9 months ago
2008
We explore a linguistically motivated approach to the problem of recognizing speculative language ("hedging") in biomedical research articles. We describe a method, whic...
BMCBI
2008
14 years 9 months ago
2008
Background: The fast growing Protein Data Bank contains the three-dimensional description of more than 45000 protein- and nucleic-acid structures today. The large majority of the ...
BMCBI
2008
14 years 9 months ago
2008
Background: MicroRNAs (miRNAs) are a set of small non-coding RNAs serving as important negative gene regulators. In animals, miRNAs turn down protein translation by binding to the...
BMCBI
2008
14 years 9 months ago
2008
Background: Prediction of protein solvent accessibility, also called accessible surface area (ASA) prediction, is an important step for tertiary structure prediction directly from...
BMCBI
2008
14 years 9 months ago
2008
: The tumour suppressor protein p53 protein has a core domain that binds DNA and is the site for most oncogenic mutations. This domain is quite unstable compared to its homologs p...