50
Voted
BMCBI
2008
15 years 26 days ago
2008
114
Voted
BMCBI
2008
15 years 26 days ago
2008
Background: Missing values frequently pose problems in gene expression microarray experiments as they can hinder downstream analysis of the datasets. While several missing value i...
130
Voted
BMCBI
2008
15 years 26 days ago
2008
Background: Single nucleotide polymorphisms (SNPs) are the most common genetic variations in the human genome and are useful as genomic markers. Oligonucleotide SNP microarrays ha...
127
Voted
BMCBI
2008
15 years 26 days ago
2008
Background: Despite considerable efforts within the microarray community for standardising data format, content and description, microarray technologies present major challenges i...
109
Voted
BMCBI
2008
15 years 26 days ago
2008
Background: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role...
81
Voted
BMCBI
2008
15 years 26 days ago
2008
Background: Outer membrane proteins (OMPs) perform diverse functional roles in Gramnegative bacteria. Identification of outer membrane proteins is an important task. Results: This...
89
Voted
BMCBI
2008
15 years 26 days ago
2008
Background: Aligning homologous non-coding RNAs (ncRNAs) correctly in terms of sequence and structure is an unresolved problem, due to both mathematical complexity and imperfect s...
86
Voted
BMCBI
2008
15 years 26 days ago
2008
Background: Virtual or in silico ligand screening combined with other computational methods is one of the most promising methods to search for new lead compounds, thereby greatly ...
103
Voted
BMCBI
2008
15 years 26 days ago
2008
Background: It is an important pre-processing step to accurately estimate missing values in microarray data, because complete datasets are required in numerous expression profile ...
129
click to vote
BMCBI
2008
15 years 26 days ago
2008
Background: High-throughput genotyping technology has enabled cost effective typing of thousands of individuals in hundred of thousands of markers for use in genome wide studies. ...