83
Voted
BMCBI
2008
15 years 26 days ago
2008
Background: Pathogen detection using DNA microarrays has the potential to become a fast and comprehensive diagnostics tool. However, since pathogen detection chips currently utili...
BMCBI
2008
15 years 26 days ago
2008
Background: Event sequences where different types of events often occur close together arise, e.g., when studying potential transcription factor binding sites (TFBS, events) of ce...
129
Voted
BMCBI
2008
15 years 26 days ago
2008
Background: Microarray experimentation requires the application of complex analysis methods as well as the use of non-trivial computer technologies to manage the resultant large d...
100
click to vote
BMCBI
2008
15 years 26 days ago
2008
Background: Mass spectrometry is a key technique in proteomics and can be used to analyze complex samples quickly. One key problem with the mass spectrometric analysis of peptides...
BMCBI
2008
15 years 26 days ago
2008
Background: Alternative RNA splicing greatly increases proteome diversity and thereby contribute to species- or tissue-specific functions. The possibility to study alternative spl...
108
Voted
BMCBI
2008
15 years 26 days ago
2008
Background: Protein sumoylation is an essential dynamic, reversible post translational modification that plays a role in dozens of cellular activities, especially the regulation o...
138
Voted
BMCBI
2008
15 years 26 days ago
2008
Background: In many research areas it is necessary to find differences between treatment groups with several variables. For example, studies of microarray data seek to find a sign...
49
Voted
BMCBI
2008
15 years 26 days ago
2008
91
Voted
BMCBI
2008
15 years 26 days ago
2008
Background: A major obstacle in treatment of HIV is the ability of the virus to mutate rapidly into drug-resistant variants. A method for predicting the susceptibility of mutated ...
114
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BMCBI
2008
15 years 26 days ago
2008
Background: In gene expression analysis, statistical tests for differential gene expression provide lists of candidate genes having, individually, a sufficiently low p-value. Howe...