CSB
2004
IEEE
13 years 10 months ago
2004
IEEE
One goal of the structural genomics initiative is the identification of new protein folds. Sequence-based structural homology prediction methods are an important means for priorit...
ATAL
2006
Springer
13 years 10 months ago
2006
Springer
Modeling dynamical systems composed of aggregations of primitive proteins is critical to the field of astrobiological science, which studies early evolutionary structures dealing ...
CICLING
2007
Springer
13 years 10 months ago
2007
Springer
In biomedical articles, terms often refer to different protein entities. For example, an arbitrary occurrence of term p53 might denote thousands of proteins across a number of spec...
CADE
1994
Springer
13 years 10 months ago
1994
Springer
Abstract. PROTEIN (PROver with a Theory Extension INterface) is a PTTPbased first order theorem prover over built-in theories. Besides various standardrefinements knownformodelelim...
RECOMB
1999
Springer
13 years 10 months ago
1999
Springer
We consider the problem of identifying common three-dimensional substructures between proteins. Our method is based on comparing the shape of the α-carbon backbone structures of ...
WABI
2001
Springer
13 years 10 months ago
2001
Springer
We describe algorithms for pattern matching and pattern learning in TOPS diagrams (formal descriptions of protein topologies). These problems can be reduced to checking for subgrap...
CSB
2002
IEEE
13 years 11 months ago
2002
IEEE
Understanding the functional significance of alternative splicing and other mechanisms that generate RNA transcript diversity is an important challenge facing modern-day molecular...
CSB
2002
IEEE
13 years 11 months ago
2002
IEEE
Assigning functions to novel proteins is one of the most important problems in the post-genomic era. Several approaches have been applied to this problem, including analyzing gene...
CSB
2003
IEEE
13 years 11 months ago
2003
IEEE
Recognition of a protein’s fold provides valuable information about its function. While many sequence-based homology prediction methods exist, an important challenge remains: tw...
CSB
2003
IEEE
13 years 11 months ago
2003
IEEE
We propose two methods for finding similarities in protein structure databases. Our techniques extract feature vectors on triplets of SSEs (Secondary Structure Elements) of prote...