The Annotation, Mapping, Expression and Network (AMEN) suite of tools for molecular systems biology

Background: High-throughput genome biological experiments yield large and multifaceted datasets that require flexible and user-friendly analysis tools to facilitate their interpretation by life scientists. Many solutions currently exist, but they are often limited to specific steps in the complex process of data management and analysis and some require extensive informatics skills to be installed and run efficiently. Results: We developed the Annotation, Mapping, Expression and Network (AMEN) software as a stand-alone, unified suite of tools that enables biological and medical researchers with basic bioinformatics training to manage and explore genome annotation, chromosomal mapping, proteinprotein interaction, expression profiling and proteomics data. The current version provides modules for (i) uploading and pre-processing data from microarray expression profiling experiments, (ii) detecting groups of significantly co-expressed genes, and (iii) searching for enrichment of functional...

• Type: Journal
• Year: 2008
• Where: BMCBI
• Authors: Frédéric Chalmel, Michael Primig
• Keywords: Biological, BMCBI 2008, Expression Profiling, User-friendly Analysis Tools