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BIBM
2007
IEEE
171views Bioinformatics» more  BIBM 2007»
13 years 11 months ago
GenMiner: Mining Informative Association Rules from Genomic Data
GENMINER is a smart adaptation of closed itemsets based association rules extraction to genomic data. It takes advantage of the novel NORDI discretization method and of the CLOSE ...
Ricardo Martínez, Claude Pasquier, Nicolas ...
BIBM
2007
IEEE
132views Bioinformatics» more  BIBM 2007»
13 years 11 months ago
A Divide-and-Conquer Implementation of Three Sequence Alignment and Ancestor Inference
In this paper, we present an algorithm to simultaneously align three biological sequences with affine gap model and infer their common ancestral sequence. Our algorithm can be fu...
Feng Yue, Jijun Tang
BIBM
2007
IEEE
13 years 11 months ago
A Geometric Representation of Protein Sequences
The amino acid sequence of a protein is the key to understanding its structure and ultimately its function in the cell. This paper addresses the fundamental issue of encoding amin...
Shengyin Gu, Olivier Poch, Bernd Hamann, Patrice K...
BIBM
2007
IEEE
159views Bioinformatics» more  BIBM 2007»
13 years 11 months ago
Predicting Future High-Cost Patients: A Real-World Risk Modeling Application
Health care data from patients in the Arizona Health Care Cost Containment System, Arizona’s Medicaid program, provides a unique opportunity to exploit state-of-the-art data pro...
Sai T. Moturu, William G. Johnson, Huan Liu
BIBM
2007
IEEE
130views Bioinformatics» more  BIBM 2007»
13 years 11 months ago
Analysis of Protein Protein Dimeric Interfaces
We analyzed the structural properties and the local surface environment of surface amino acid residues of proteins using a large, non-redundant dataset of 2383 protein chains in d...
Feihong Wu, Fadi Towfic, Drena Dobbs, Vasant Honav...
BIBE
2007
IEEE
148views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
A New Smoothing Model for Analyzing Array CGH Data
—Array based Comparative Genomic Hybridization (CGH) is a molecular cytogenetic method for the detection of chromosomal imbalances and it has been extensively used for studying c...
Nha Nguyen, Heng Huang, Soontorn Oraintara, An P. ...
BIBE
2007
IEEE
134views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
Bottom-Up Multiple Row Addition Algorithms for the Biclustering-Problem
Abstract—The discovery of locally and significantly correlated subpatterns within a two-dimensional dataset has recently become quite popular and is amongst others addressed by ...
Hyung-Won Koh, Lars Hildebrand
BIBE
2007
IEEE
110views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
Discrete Methods for Association Search and Status Prediction in Genotype Case-Control Studies
Abstract—Recent improvements in high-throughput genotyping technology make possible genome-wide association studies and status prediction (classification) for common complex dis...
Dumitru Brinza, Alexander Zelikovsky
BIBE
2007
IEEE
154views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
A Compartmentalized Approach to the Assembly of Physical Maps
We propose a novel compartmentalized method for the assembly of physical maps from fingerprinted clones. Our assembler exploits the presence of genetic markers at the global leve...
Serdar Bozdag, Timothy J. Close, Stefano Lonardi
BIBE
2007
IEEE
115views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
Semiparametric RMA Background-Correction for Oligonucleotide Arrays
—Microarray technology has provided an opportunity to simultaneously monitor the expression levels of a large number of genes in response to intentional perturbations. A necessar...
Ionut Bebu, Françoise Seillier-Moiseiwitsch...