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BIBE
2007
IEEE
132views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
Morphometric Analysis of Hippocampal Shape in Mild Cognitive Impairment: An Imaging Genetics Study
—A computational framework is presented for surface based morphometry to localize shape changes between groups of 3D objects. It employs the spherical harmonic (SPHARM) method fo...
Li Shen, Andrew J. Saykin, Moo K. Chung, Heng Huan...
BIBE
2007
IEEE
176views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
HICCUP: Hierarchical Clustering Based Value Imputation using Heterogeneous Gene Expression Microarray Datasets
Abstract—A novel microarray value imputation method, HICCUP1 , is presented. HICCUP improves upon existing value imputation methods in the several ways. (1) By judiciously integr...
Qiankun Zhao, Prasenjit Mitra, Dongwon Lee, Jaewoo...
BIBE
2007
IEEE
174views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
Shortest Path Approaches for the Longest Common Subsequence of a Set of Strings
—We investigate the k-LCS problem that is finding a longest common subsequence (LCS) for k given input strings. The problem is known to have practical solutions for k = 2, but f...
Marina Barsky, Ulrike Stege, Alex Thomo, Chris Upt...
BIBE
2007
IEEE
114views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
A Hierarchical Grow-and-Match Algorithm for Backbone Resonance Assignments Given 3D Structure
Abstract—This paper develops an algorithm for NMR backbone resonance assignment given a 3D structure and a set of relatively sparse 15 N-edited NMR data, with the through-space 1...
Fei Xiong, Chris Bailey-Kellogg
BIBE
2007
IEEE
101views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
A Robotic System for Real-time Tumor Manipulation During Image guided Breast Biopsy
Breast biopsy guided by imaging techniques such as ultrasound is widely used to evaluate suspicious masses within the breast. Currently, ultrasound imaging does not allow live guid...
Vishnu Mallapragada, Nilanjan Sarkar, Tarun Kanti ...
BIBE
2007
IEEE
108views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
Using Parsimony to Guide Maximum Likelihood Searches
—The performance of maximum likelihood searches can be boosted by using the most parsimonious tree as a starting point for the search. The time spent in performing the parsimony ...
Kenneth Sundberg, Timothy O'Connor, Hyrum Carroll,...
BIBE
2007
IEEE
110views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
Toward Petascale Simulation of Cellular Microphysiology
Abstract-MCell is a Monte Carlo simulator of cell microphysiology, and the scalable variant can be used to study challenging problems of interest to the biological community. MCell...
Scott B. Baden, Terrence J. Sejnowski, Thomas M. B...
BIBE
2007
IEEE
108views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
Intrinsically Disordered Proteins: Predictions and Applications
A. Keith Dunker, Christopher J. Oldfield, Jingwei ...
BIBE
2007
IEEE
142views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
An HV-SVM Classifier to Infer TF-TF Interactions Using Protein Domains and GO Annotations
—Interactions between transcription factors (TFs) are necessary for deciphering the complex mechanisms of transcription regulation in eukaryotes. In this paper, we proposed a nov...
Xiaoli Li, Jun-Xiang Lee, Bharadwaj Veeravalli, Se...
BIBE
2007
IEEE
155views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
Partial Mixture Model for Tight Clustering in Exploratory Gene Expression Analysis
Abstract—In this paper we demonstrate the inherent robustness of minimum distance estimator that makes it a potentially powerful tool for parameter estimation in gene expression ...
Yinyin Yuan, Chang-Tsun Li