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ISMB
1996
13 years 6 months ago
Ontological Foundations for Biology Knowledge Models
Carole D. Hafner, Natalya Fridman Noy
ISMB
1996
13 years 6 months ago
Gene Prediction by Pattern Recognition and Homology Search
This paper presents an algorithm for combining pattern recognition-based exon prediction and database homologysearch in gene model construction. Thegoal is to use homologousgeneso...
Ying Xu, Edward C. Uberbacher
ISMB
1996
13 years 6 months ago
The Megaprior Heuristic for Discovering Protein Sequence Patterns
Several computeralgorithms for discovering patterns in groups of protein sequences are in use that are basedon fitting the parametersof a statistical model to a group of related s...
Timothy L. Bailey, Michael Gribskov
ISMB
1996
13 years 6 months ago
Discovering Empirically Conserved Amino Acid Substitution Groups in Databases of Protein Families
Thispaperintroducesa methodfor identifyingempirically conservedaminoacid substitution groups.In contrast with existing approachesthat viewaminoacid substitution as a pairwisepheno...
Thomas D. Wu, Douglas L. Brutlag
ISMB
1996
13 years 6 months ago
Discovering Patterns and Subfamilies in Biosequences
Weconsider the problemof automaticdiscoveryof patterns and the corresponding subfamilies in a set of biosequences. Thesequences are unaligned and may contain noise of unknownlevel...
Alvis Brazma, Inge Jonassen, Esko Ukkonen, Jaak Vi...
ISMB
1996
13 years 6 months ago
Improving the Quality of Automatic DNA Sequence Assembly Using Fluorescent Trace-Data Classifications
Virtually all large-scale sequencing projects use automatic sequence-assembly programs to aid in the determination of DNA sequences. The computer-generated assemblies require subs...
Carolyn F. Allex, Schuyler F. Baldwin, Jude W. Sha...
ISMB
1997
13 years 6 months ago
Bayesian Adaptive Alignment and Inference
Sequencealignmentwithoutthe specification of gap penaltiesor a scoringmatrixis attainedbyusing Bayesianinferenceanda recursivealgorithm.Thisprocedure’srecursivealgorithmsumsover...
Jun Zhu, Jun S. Liu, Charles E. Lawrence
ISMB
1997
13 years 6 months ago
Functional Prediction of B. subtilis Genes from Their Regulatory Sequences
In bacterial cells, gene expression is regulated by multiple sigma factors, each of which has its promoter specificity, according to their conditions. Thus, if we can discriminate...
Tetsushi Yada, Yasushi Totoki, Takahiro Ishii, Ken...
ISMB
1997
13 years 6 months ago
Inferring Gene Structures in Genomic Sequences Using Pattern Recognition and Expressed Sequence Tags
Abstract.) Ying Xu, Richard J. MuraF, and Edward C. Uberbacher Computer Science and Mathematics Division and tLife Sciences Division Computational methods for gene identification ...
Ying Xu, Richard J. Mural, Edward C. Uberbacher
ISMB
1997
13 years 6 months ago
Better Cutters for Protein Mass Fingerprinting: Preliminary Findings
Michael J. Wise, Tim Littlejohn, Ian Humphery-Smit...