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RECOMB
2008
Springer
9 years 6 months ago
An Integrative Network Approach to Map the Transcriptome to the Phenome
Michael R. Mehan, Juan Nunez-Iglesias, Mrinal Kala...
RECOMB
2008
Springer
9 years 6 months ago
Algorithms for Joint Optimization of Stability and Diversity in Planning Combinatorial Libraries of Chimeric Proteins
Abstract. In engineering protein variants by constructing and screening combinatorial libraries of chimeric proteins, two complementary and competing goals are desired: the new pro...
Wei Zheng, Alan M. Friedman, Chris Bailey-Kellogg
RECOMB
2008
Springer
9 years 6 months ago
High-Resolution Modeling of Cellular Signaling Networks
A central challenge in systems biology is the reconstruction of biological networks from high-throughput data sets. A particularly difficult case of this is the inference of dynami...
Michael Baym, Chris Bakal, Norbert Perrimon, Bonni...
RECOMB
2008
Springer
9 years 6 months ago
Rapid and Accurate Protein Side Chain Prediction with Local Backbone Information
High-accuracy protein structure modeling demands accurate and very fast side chain prediction since such a procedure must be repeatedly called at each step of structure refinement....
Jing Zhang, Xin Gao, Jinbo Xu, Ming Li
RECOMB
2008
Springer
9 years 6 months ago
On the Inference of Ancestries in Admixed Populations
Sriram Sankararaman, Gad Kimmel, Eran Halperin, Mi...
RECOMB
2008
Springer
9 years 6 months ago
CompostBin: A DNA Composition-Based Algorithm for Binning Environmental Shotgun Reads
A major hindrance to studies of microbial diversity has been that the vast majority of microbes cannot be cultured in the laboratory and thus are not amenable to traditional method...
Sourav Chatterji, Ichitaro Yamazaki, Zhaojun Bai, ...
RECOMB
2008
Springer
9 years 6 months ago
Constructing Treatment Portfolios Using Affinity Propagation
A key problem of interest to biologists and medical researchers is the selection of a subset of queries or treatments that provide maximum utility for a population of targets. For ...
Delbert Dueck, Brendan J. Frey, Nebojsa Jojic, Vla...
RECOMB
2008
Springer
9 years 6 months ago
A Fast, Alignment-Free, Conservation-Based Method for Transcription Factor Binding Site Discovery
As an increasing number of eukaryotic genomes are being sequenced, comparative studies aimed at detecting regulatory elements in intergenic sequences are becoming more prevalent. M...
Raluca Gordân, Leelavati Narlikar, Alexander...
RECOMB
2008
Springer
9 years 6 months ago
Constructing Level-2 Phylogenetic Networks from Triplets
Leo van Iersel, Judith Keijsper, Steven Kelk, Leen...
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