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RECOMB
2007
Springer
9 years 6 months ago
Reconstructing the Topology of Protein Complexes
Abstract. Recent advances in high-throughput experimental techniques have enabled the production of a wealth of protein interaction data, rich in both quantity and variety. While t...
Allister Bernard, David S. Vaughn, Alexander J. Ha...
RECOMB
2007
Springer
9 years 6 months ago
Framework for Identifying Common Aberrations in DNA Copy Number Data
High-resolution array comparative genomic hybridization (aCGH) provides exon-level mapping of DNA aberrations in cells or tissues. Such aberrations are central to carcinogenesis an...
Amir Ben-Dor, Doron Lipson, Anya Tsalenko, Mark Re...
RECOMB
2007
Springer
9 years 6 months ago
Production-Passage-Time Approximation: A New Approximation Method to Accelerate the Simulation Process of Enzymatic Reactions
Abstract. Given the substantial computational requirements of stochastic simulation, approximation is essential for efficient analysis of any realistic biochemical system. This pap...
Hiroyuki Kuwahara, Chris J. Myers
RECOMB
2007
Springer
9 years 6 months ago
Tools for Simulating and Analyzing RNA Folding Kinetics
Xinyu Tang, Shawna L. Thomas, Lydia Tapia, Nancy M...
RECOMB
2007
Springer
9 years 6 months ago
QNet: A Tool for Querying Protein Interaction Networks
Molecular interaction databases can be used to study the evolution of molecular pathways across species. Querying such pathways is a challenging computational problem, and recent e...
Banu Dost, Tomer Shlomi, Nitin Gupta 0002, Eytan R...
RECOMB
2007
Springer
9 years 6 months ago
Support Vector Training of Protein Alignment Models
Abstract. Sequence to structure alignment is an important step in homology modeling of protein structures. Incorporation of features like secondary structure, solvent accessibility...
Chun-Nam John Yu, Thorsten Joachims, Ron Elber, Ja...
RECOMB
2007
Springer
9 years 6 months ago
Association Mapping of Complex Diseases with Ancestral Recombination Graphs: Models and Efficient Algorithms
Association, or LD (linkage disequilibrium), mapping is an intensely-studied approach to gene mapping (genome-wide or in candidate regions) that is widely hoped to be able to effic...
Yufeng Wu
RECOMB
2008
Springer
9 years 6 months ago
Estimating the Relative Contributions of New Genes from Retrotransposition and Segmental Duplication Events during Mammalian Evo
Gene duplication has long been recognized as a major force in genome evolution and has recently been recognized as an important source of individual variation. For many years the o...
Jin Jun, Paul Ryvkin, Edward Hemphill, Ion I. Mand...
RECOMB
2008
Springer
9 years 6 months ago
Limitations of Pseudogenes in Identifying Gene Losses
The loss of previously established genes has been proposed as a major force in evolutionary change. While the sequencing of many new species offers the opportunity to identify case...
James C. Costello, Mira V. Han, Matthew W. Hahn
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