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BIOCOMP
2006
10 years 1 months ago
Finding Molecular Signature of Prostate Cancer: An Algorithmic Approach
123 African American men in America are 65% more likely to develop prostate cancer and are two to three times more likely to die of the disease than Caucasian men [1]. While resear...
Patrick Bobbie, Renee Reams, Sandra Suther, C. Per...
BIOCOMP
2006
10 years 1 months ago
Learning Genetic and Gene Bayesian Networks with Hidden Variables: Bilayer Verification Algorithm
To improve the recovery of gene-gene and marker-gene (eQTL) interaction networks from microarray and genetic data, we propose a new procedure for learning Bayesian networks. This a...
Jason E. Aten
BIOCOMP
2006
10 years 1 months ago
Evaluation of a Novel Metric for Quality Control in an RNA Interference High Throughput Screening Assay
The application of genome scale RNA interference (RNAi) relies on the development of high quality RNAi high throughput screening (HTS) assays. An important quality control (QC) ch...
Xiaohua Douglas Zhang, Amy S. Espeseth, Namjin Chu...
BIOCOMP
2006
10 years 1 months ago
An Approach to Selecting Putative RNA Motifs Using MDL Principle
The history of molecular biology is punctuated by a series of discoveries demonstrating the surprising breadth of biological roles of ribonucleic acid (RNA). An ensemble of evoluti...
Mohammad Anwar, Marcel Turcotte
BIOCOMP
2006
10 years 1 months ago
Dynamic Bayesian Network (DBN) with Structure Expectation Maximization (SEM) for Modeling of Gene Network from Time Series Gene
Exploring gene regulatory network is a key topic in molecular biology. In this paper, we present a new dynamic Bayesian network (DBN) framework embedded with structural expectatio...
Yu Zhang, Zhidong Deng, Hongshan Jiang, Peifa Jia
BIOCOMP
2006
10 years 1 months ago
Fusion genes as putative microbial drug targets in H. pylori
Fusion genes have been reported as a means of enabling the development of novel or enhanced functions. In this report, we analyzed fusion genes in the genomes of two Helicobacter ...
Meena K. Sakharkar, Kishore R. Sakharkar, Vincent ...
BIOCOMP
2006
10 years 1 months ago
Computer-Aided Cytogenetic Method of Breast Cancer Diagnosis, Part II - Test Criteria
In this part we describe the statistical test criteria which are used in Part I in the construction of computer-aided cytogenetic method of breast cancer diagnosis.
Roman Andrushkiw, Dmitry Klyushin, Ekaterina Golub...
BIOCOMP
2006
10 years 1 months ago
Reducing Harmful Effects Of Road Excitations On Human Health By Designing Car Active Suspension Systems
act Nowadays people are strongly dependent on cars for doing their tasks, but they usually are not aware of hazards which are awaiting them. For instance, since people travel with ...
Sara Sharifi Sedeh, Reza Sharifi Sedeh, Keivan Nav...
BIOCOMP
2006
10 years 1 months ago
X-Ray Powder Diffraction Metrics
To compare sample data from x-ray diffraction a suitable metric is developed to evaluate the similarity (or dissimilarity) between samples and to compare it to a references. The m...
George Runger, Kelly Canter, John Twist, David Ros...
BIOCOMP
2007
10 years 1 months ago
Biomarker Discovery Across Annotated and Unannotated Microarray Datasets Using Semi-Supervised Learning
The growing body of DNA microarray data has the potential to advance our understanding of the molecular basis of disease. However annotating microarray datasets with clinically us...
Cole Harris, Noushin Ghaffari
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