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BMCBI
2005
99views more  BMCBI 2005»
13 years 4 months ago
Super paramagnetic clustering of protein sequences
Background: Detection of sequence homologues represents a challenging task that is important for the discovery of protein families and the reliable application of automatic annota...
Igor V. Tetko, Axel Facius, Andreas Ruepp, Hans-We...
BMCBI
2005
98views more  BMCBI 2005»
13 years 4 months ago
DCD - a novel plant specific domain in proteins involved in development and programmed cell death
Background: Recognition of microbial pathogens by plants triggers the hypersensitive reaction, a common form of programmed cell death in plants. These dying cells generate signals...
Raimund Tenhaken, Tobias Doerks, Peer Bork
BMCBI
2005
104views more  BMCBI 2005»
13 years 4 months ago
Wildfire: distributed, Grid-enabled workflow construction and execution
Background: We observe two trends in bioinformatics: (i) analyses are increasing in complexity, often requiring several applications to be run as a workflow; and (ii) multiple CPU...
Francis Tang, Ching Lian Chua, Liang-Yoong Ho, Yun...
BMCBI
2005
140views more  BMCBI 2005»
13 years 4 months ago
Dissecting systems-wide data using mixture models: application to identify affected cellular processes
Background: Functional analysis of data from genome-scale experiments, such as microarrays, requires an extensive selection of differentially expressed genes. Under many condition...
J. Peter Svensson, Renée X. de Menezes, Ing...
BMCBI
2005
96views more  BMCBI 2005»
13 years 4 months ago
Comparison of codon usage measures and their applicability in prediction of microbial gene expressivity
Background: There are a number of methods (also called: measures) currently in use that quantify codon usage in genes. These measures are often influenced by other sequence proper...
Fran Supek, Kristian Vlahovicek
BMCBI
2005
152views more  BMCBI 2005»
13 years 4 months ago
Ranking the whole MEDLINE database according to a large training set using text indexing
Background: The MEDLINE database contains over 12 million references to scientific literature, ut 3/4 of recent articles including an abstract of the publication. Retrieval of ent...
Brian P. Suomela, Miguel A. Andrade
BMCBI
2005
125views more  BMCBI 2005»
13 years 4 months ago
DIALIGN-T: An improved algorithm for segment-based multiple sequence alignment
Background: We present a complete re-implementation of the segment-based approach to multiple protein alignment that contains a number of improvements compared to the previous ver...
Amarendran R. Subramanian, Jan Weyer-Menkhoff, Mic...
BMCBI
2005
120views more  BMCBI 2005»
13 years 4 months ago
Harshlight: a "corrective make-up" program for microarray chips
Background: Microscopists are familiar with many blemishes that fluorescence images can have due to dust and debris, glass flaws, uneven distribution of fluids or surface coatings...
Mayte Suárez-Fariñas, Maurizio Pelle...
BMCBI
2005
112views more  BMCBI 2005»
13 years 4 months ago
"Harshlighting" small blemishes on microarrays
Background: Microscopists are familiar with many blemishes that fluorescence images can have due to dust and debris, glass flaws, uneven distribution of fluids or surface coatings...
Mayte Suárez-Fariñas, Asifa Haider, ...
BMCBI
2005
125views more  BMCBI 2005»
13 years 4 months ago
Multiple sequence alignments of partially coding nucleic acid sequences
Background: High quality sequence alignments of RNA and DNA sequences are an important prerequisite for the comparative analysis of genomic sequence data. Nucleic acid sequences, ...
Roman R. Stocsits, Ivo L. Hofacker, Claudia Fried,...