Sciweavers

CSB
2005
IEEE
103views Bioinformatics» more  CSB 2005»
13 years 10 months ago
ECOME: A simple model for an evolving consumption web
ECOME is an interactive, graph-based model for simulating an evolving, closed consumption web. It demonstrates the fundamental behavior of a global ecosystem over evolutionary tim...
Christopher Bystroff, Sam DeLuca, Carl N. McDaniel
CSB
2005
IEEE
109views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Patterns of Gene Deletion following Genome Duplication in Yeast
Whole genome duplication (WGD) is followed by massive duplicate deletion that reorganizes gene adjacencies. We compare the deletion patterns and adjacency reorganization following...
Jake K. Byrnes, Wen-Hsiung Li
CSB
2005
IEEE
120views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Chemical Structure-Activity Relationship Visualization Using Structure Activity Maps
This study shows an effective way to explore and visualize the structure-activity relationships (SARs) of flavonoids with antioxidant activity using structure- activity maps (SAMs...
Weiguo Fan, Xin Lin, Yu-Wei Hsieh, Johnnie W. Bake...
CSB
2005
IEEE
116views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Oscillatory dynamics in the mitogen-activated protein kinase cascade
We have used quantitative modeling of signaling networks to show that the mitogen-activated protein kinase cascade — a highly-conserved signaling network in eukaryotes — can f...
K.-H. Chiam, Vipul Bhargava, Gunaretnam Rajagopal
CSB
2005
IEEE
110views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Maximum Sequence Alignment Fails to Predict Off-targeted Gene Regulation by RNAi
We have employed various sequence alignment algorithms and scoring techniques to determine whether current computational tools accurately predict genes that will be off-targeted b...
Amanda Birmingham, Emily M. Anderson, William S. M...
CSB
2005
IEEE
182views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Bacterial Whole Genome Phylogeny Using Proteome Comparison and Optimal Reversal Distance
Traditional phylogenetic tree reconstruction is based on point mutations of a single gene. This approach is hardly suitable for genomes whose genes are almost identical and hardly...
Noppadon Khiripet
CSB
2005
IEEE
139views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Open Microscopy Environment
High-throughput scoring of image-based biological assays heavily depends on the extraction of quantitative numerical information from microscopy images. This paper describes how t...
Ilya G. Goldberg
CSB
2005
IEEE
140views Bioinformatics» more  CSB 2005»
13 years 10 months ago
HIV Structural and Biothermodynamics Databases: a Resource for the Pharmaceutical and Biotechnology Industry
Federal agencies, academia and industries have invested heavily in the development of structural and biothermodynamic data. However, the data are still largely distributed over se...
Talapady N. Bhat, Yadu B. Tewari, Henry Rodriguez,...
CSB
2005
IEEE
124views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Multi-Scale Hierarchical Structure Prediction of Helical Transmembrane Proteins
As the first step toward a multi-scale, hierarchical computational approach for membrane protein structure prediction, the packing of transmembrane helices was modeled at the resi...
Zhong Chen, Ying Xu
CSB
2005
IEEE
139views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Predicting gene function by combining expression and interaction data
In this study we combined the spurious protein interaction data from the Database of Interacting Proteins with the recently published gene expression data of S. cerevisiae grown w...
Rogier J. P. van Berlo, Lodewyk F. A. Wessels, S. ...