The directed evolution of proteins, using an in vitro domainal shuffling strategy was proposed in (J. Kolkman and W. Stemmer, Nat. Biotech. 19, 423 (2001). Due to backhybridization...
John A. Rose, Russell J. Deaton, Masami Hagiya, Ak...
In this paper we present a method for protein structure comparison that is based on indexing. Unlike most methods using indexing, ours does not use invariants of the C atoms of th...
Concettina Guerra, Stefano Lonardi, Giuseppe Zanot...
While modern evolutionary theory has emphasized the role of neutral evolution, protein biochemistry and biophysics has interpreted the properties of proteins as largely resulting f...
Proteins are the driving force in development (embryogenesis) and the immune system. Here we describe how a model of proteins designed for evolutionary development in computers can...
Motivation: With the increasing availability of protein structures, the generation of biologically meaningful 3D patterns from the simultaneous alignment of several protein struct...
The process by which a cell senses and responds to its environment, as in signal transduction, is often mediated by a network of protein-protein interactions, in which proteins co...
James R. Faeder, Michael L. Blinov, William S. Hla...
A key issue in the study of protein signaling networks is understanding the relationships among proteins in the network. Understanding these relationships in the context of a netw...
Edward E. Allen, Jacquelyn S. Fetrow, David J. Joh...
In this study we combined the spurious protein interaction data from the Database of Interacting Proteins with the recently published gene expression data of S. cerevisiae grown w...
Rogier J. P. van Berlo, Lodewyk F. A. Wessels, S. ...
Phylogenetic profiles of proteins − strings of ones and zeros encoding respectively the presence and absence of proteins in a group of genomes − have recently been used to iden...
Proteins are large organic compounds made of amino acids arranged in a linear chain (primary structure). Most proteins fold into unique threedimensional (3D) structures called inte...
Marco Vassura, Luciano Margara, Filippo Medri, Pie...