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DNA
2001
Springer
125views Bioinformatics» more  DNA 2001»
13 years 9 months ago
PNA-mediated Whiplash PCR
The directed evolution of proteins, using an in vitro domainal shuffling strategy was proposed in (J. Kolkman and W. Stemmer, Nat. Biotech. 19, 423 (2001). Due to backhybridization...
John A. Rose, Russell J. Deaton, Masami Hagiya, Ak...
3DPVT
2002
IEEE
121views Visualization» more  3DPVT 2002»
13 years 10 months ago
Analysis of Secondary Structure Elements of Proteins Using Indexing Techniques
In this paper we present a method for protein structure comparison that is based on indexing. Unlike most methods using indexing, ours does not use invariants of the C atoms of th...
Concettina Guerra, Stefano Lonardi, Giuseppe Zanot...
ICCS
2004
Springer
13 years 10 months ago
Evolutionary Perspectives on Protein Thermodynamics
While modern evolutionary theory has emphasized the role of neutral evolution, protein biochemistry and biophysics has interpreted the properties of proteins as largely resulting f...
Richard A. Goldstein
ICARIS
2004
Springer
13 years 10 months ago
A Fractal Immune Network
Proteins are the driving force in development (embryogenesis) and the immune system. Here we describe how a model of proteins designed for evolutionary development in computers can...
Peter J. Bentley, Jon Timmis
GCB
2005
Springer
117views Biometrics» more  GCB 2005»
13 years 10 months ago
Generation of 3D templates of active sites of proteins with rigid prosthetic groups
Motivation: With the increasing availability of protein structures, the generation of biologically meaningful 3D patterns from the simultaneous alignment of several protein struct...
Jean-Christophe Nebel
SAC
2005
ACM
13 years 10 months ago
Graphical rule-based representation of signal-transduction networks
The process by which a cell senses and responds to its environment, as in signal transduction, is often mediated by a network of protein-protein interactions, in which proteins co...
James R. Faeder, Michael L. Blinov, William S. Hla...
ACMSE
2005
ACM
13 years 10 months ago
Heuristics for dependency conjectures in proteomic signaling pathways
A key issue in the study of protein signaling networks is understanding the relationships among proteins in the network. Understanding these relationships in the context of a netw...
Edward E. Allen, Jacquelyn S. Fetrow, David J. Joh...
CSB
2005
IEEE
139views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Predicting gene function by combining expression and interaction data
In this study we combined the spurious protein interaction data from the Database of Interacting Proteins with the recently published gene expression data of S. cerevisiae grown w...
Rogier J. P. van Berlo, Lodewyk F. A. Wessels, S. ...
SAC
2006
ACM
13 years 11 months ago
Protein classification using transductive learning on phylogenetic profiles
Phylogenetic profiles of proteins − strings of ones and zeros encoding respectively the presence and absence of proteins in a group of genomes − have recently been used to iden...
Roger A. Craig, Li Liao
ISBRA
2007
Springer
13 years 11 months ago
Reconstruction of 3D Structures from Protein Contact Maps
Proteins are large organic compounds made of amino acids arranged in a linear chain (primary structure). Most proteins fold into unique threedimensional (3D) structures called inte...
Marco Vassura, Luciano Margara, Filippo Medri, Pie...