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BMCBI
2005
124views more  BMCBI 2005»
9 years 1 months ago
Probabilistic annotation of protein sequences based on functional classifications
: One of the most evident achievements of bioinformatics is the development of methods that transfer biological knowledge from characterised proteins to uncharacterised sequences. ...
Emmanuel D. Levy, Christos A. Ouzounis, Walter R. ...
BMCBI
2005
117views more  BMCBI 2005»
9 years 1 months ago
An SVM-based system for predicting protein subnuclear localizations
Background: The large gap between the number of protein sequences in databases and the number of functionally characterized proteins calls for the development of a fast computatio...
Zhengdeng Lei, Yang Dai
BMCBI
2005
136views more  BMCBI 2005»
9 years 1 months ago
Automatic detection of false annotations via binary property clustering
Background: Computational protein annotation methods occasionally introduce errors. Falsepositive (FP) errors are annotations that are mistakenly associated with a protein. Such f...
Noam Kaplan, Michal Linial
BMCBI
2005
86views more  BMCBI 2005»
9 years 1 months ago
Confirmation of human protein interaction data by human expression data
Background: With microarray technology the expression of thousands of genes can be measured simultaneously. It is well known that the expression levels of genes of interacting pro...
Andreas Hahn, Jörg Rahnenführer, Priti T...
BMCBI
2005
115views more  BMCBI 2005»
9 years 1 months ago
SUPERFICIAL - Surface mapping of proteins via structure-based peptide library design
Background: The determination of protein surfaces and the detection of binding sites are essential to our understanding of protein-protein interactions. Such binding sites can be ...
Andrean Goede, Ines S. Jaeger, Robert Preissner
BMCBI
2005
90views more  BMCBI 2005»
9 years 1 months ago
TMB-Hunt: An amino acid composition based method to screen proteomes for beta-barrel transmembrane proteins
Background: Beta-barrel transmembrane (bbtm) proteins are a functionally important and diverse group of proteins expressed in the outer membranes of bacteria (both gram negative a...
Andrew G. Garrow, Alison Agnew, David R. Westhead
BMCBI
2005
93views more  BMCBI 2005»
9 years 1 months ago
SPdb - a signal peptide database
Background: The signal peptide plays an important role in protein targeting and protein translocation in both prokaryotic and eukaryotic cells. This transient, short peptide seque...
Khar Heng Choo, Tin Wee Tan, Shoba Ranganathan
IJDMB
2007
110views more  IJDMB 2007»
9 years 1 months ago
Transductive learning with EM algorithm to classify proteins based on phylogenetic profiles
: Phylogenetic profiles of proteins  strings of ones and zeros encoding respectively the presence and absence of proteins in a group of genomes  have recently been used to id...
Roger A. Craig, Li Liao
IJBRA
2007
88views more  IJBRA 2007»
9 years 1 months ago
Finding molecular complexes through multiple layer clustering of protein interaction networks
: Clustering protein-protein interaction networks (PINs) helps to identify complexes that guide the cell machinery. Clustering algorithms often create a flat clustering, without co...
Bill Andreopoulos, Aijun An, Xiangji Huang, Xiaoga...
PR
2006
110views more  PR 2006»
9 years 1 months ago
Classifying protein sequences using hydropathy blocks
The annotation of proteins can be achieved by classifying the protein of interest into a certain known protein family to induce its functional and structural features. This paper ...
De-Shuang Huang, Xing-Ming Zhao, Guang-Bin Huang, ...
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