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BMCBI
2011
8 years 6 months ago
A Computational Framework for Proteome-Wide Pursuit and Prediction of Metalloproteins using ICP-MS and MS/MS Data
Background: Metal-containing proteins comprise a diverse and sizable category within the proteomes of organisms, ranging from proteins that use metals to catalyze reactions to pro...
W. Andrew Lancaster, Jeremy L. Praissman, Farris L...
BMCBI
2011
8 years 6 months ago
NClassG+: A classifier for non-classically secreted Gram-positive bacterial proteins
Background: Most predictive methods currently available for the identification of protein secretion mechanisms have focused on classically secreted proteins. In fact, only two met...
Daniel Restrepo-Montoya, Camilo Pino, Luis F. Ni&n...
BMCBI
2010
107views more  BMCBI 2010»
8 years 6 months ago
Interaction prediction and classification of PDZ domains
Background: PDZ domain is a well-conserved, structural protein domain found in hundreds of signaling proteins that are otherwise unrelated. PDZ domains can bind to the C-terminal ...
Sibel Kalyoncu, Ozlem Keskin, Attila Gürsoy
BMCBI
2010
137views more  BMCBI 2010»
8 years 6 months ago
The ancient history of the structure of ribonuclease P and the early origins of Archaea
Background: Ribonuclease P is an ancient endonuclease that cleaves precursor tRNA and generally consists of a catalytic RNA subunit (RPR) and one or more proteins (RPPs). It repre...
Feng-Jie Sun, Gustavo Caetano-Anollés
BCB
2010
125views Bioinformatics» more  BCB 2010»
8 years 6 months ago
Protein structure alignment using elastic shape analysis
In this paper we present a method for flexible protein structure alignment based on elastic shape analysis of backbones, in a manner that can incorporate different characteristics...
Wei Liu, Anuj Srivastava, Jinfeng Zhang
BICOB
2009
Springer
8 years 9 months ago
A Biclustering Method to Discover Co-regulated Genes Using Diverse Gene Expression Datasets
We propose a two-step biclustering approach to mine co-regulation patterns of a given reference gene to discover other genes that function in a common biological process. Currently...
Doruk Bozdag, Jeffrey D. Parvin, Ümit V. &Cce...
BIBM
2010
IEEE
157views Bioinformatics» more  BIBM 2010»
8 years 9 months ago
Decomposing PPI networks for complex discovery
Abstract--Protein complexes are important for understanding principles of cellular organization and functions. With the availability of large amounts of high-throughput proteinprot...
Guimei Liu, Chern Han Yong, Limsoon Wong, Hon Nian...
IJBRA
2010
121views more  IJBRA 2010»
8 years 10 months ago
Mining Cytochrome b561 proteins from plant genomes
—Cytochrome b561 (Cyt-b561) proteins play important functions in plants such as anti-toxin defense reactions, growth and development, and prevention of damage to plants from exce...
Stephen O. Opiyo, Etsuko N. Moriyama
NAR
2007
96views more  NAR 2007»
8 years 11 months ago
New developments in the InterPro database
InterPro is an integrated resource for protein families, domains and functional sites, which integrates the following protein signature databases: PROSITE, PRINTS, ProDom, Pfam, S...
Nicola J. Mulder, Rolf Apweiler, Teresa K. Attwood...
NAR
2007
260views more  NAR 2007»
8 years 11 months ago
WoLF PSORT: protein localization predictor
WoLF PSORT is an extension of the PSORT II program for protein subcellular location prediction. WoLF PSORT converts protein amino acid sequences into numerical localization featur...
Paul Horton, Keun-Joon Park, Takeshi Obayashi, Nao...
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