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BMCBI
2011
10 years 8 months ago
ATAQS: A computational software tool for high throughput transition optimization and validation for selected reaction monitoring
Background: Since its inception, proteomics has essentially operated in a discovery mode with the goal of identifying and quantifying the maximal number of proteins in a sample. I...
Mi-Youn K. Brusniak, Sung-Tat Kwok, Mark Christian...
BMCBI
2010
161views more  BMCBI 2010»
10 years 10 months ago
Addressing the Challenge of Defining Valid Proteomic Biomarkers and Classifiers
Background: The purpose of this manuscript is to provide, based on an extensive analysis of a proteomic data set, suggestions for proper statistical analysis for the discovery of ...
Mohammed Dakna, Keith Harris, Alexandros Kalousis,...
BMCBI
2004
228views more  BMCBI 2004»
11 years 1 months ago
An XML standard for the dissemination of annotated 2D gel electrophoresis data complemented with mass spectrometry results
Background: Many proteomics initiatives require a seamless bioinformatics integration of a range of analytical steps between sample collection and systems modeling immediately ass...
Romesh Stanislaus, Liu Hong Jiang, Martha Swartz, ...
NAR
2008
107views more  NAR 2008»
11 years 1 months ago
ISPIDER Central: an integrated database web-server for proteomics
Despite the growing volumes of proteomic data, integration of the underlying results remains problematic owing to differences in formats, data captured, protein accessions and ser...
Jennifer A. Siepen, Khalid Belhajjame, Julian N. S...
BMCBI
2008
100views more  BMCBI 2008»
11 years 1 months ago
PatternLab for proteomics: a tool for differential shotgun proteomics
Background: A goal of proteomics is to distinguish between states of a biological system by identifying protein expression differences. Liu et al. demonstrated a method to perform...
Paulo C. Carvalho, Juliana S. G. Fischer, Emily I....
BMCBI
2008
219views more  BMCBI 2008»
11 years 1 months ago
Classification of premalignant pancreatic cancer mass-spectrometry data using decision tree ensembles
Background: Pancreatic cancer is the fourth leading cause of cancer death in the United States. Consequently, identification of clinically relevant biomarkers for the early detect...
Guangtao Ge, G. William Wong
BIB
2008
101views more  BIB 2008»
11 years 1 months ago
Information quality in proteomics
Proteomics, the study of the protein complement of a biological system, is generating increasing quantities of data from rapidly developing technologies employed in a variety of d...
David Stead, Norman W. Paton, Paolo Missier, Suzan...
BIBE
2008
IEEE
11 years 7 months ago
VIP: Visualization of integrated proteomics data
—The post-genomic era is characterized by the rapid data accumulation leading to unwieldy and large volumes of biological data. The proteomics results (large sets of identified p...
Eugenia G. Giannopoulou, Giorgos Lepouras, Elias S...

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adambyronPostdoctoral
University of Manchester
adambyron
A biochemist and cell biologist using proteomic approaches to investigate mechanisms of cell adhesion.
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