184
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WABI
14 years 11 months ago
2010 Springer
Abstract. We present three heuristic strategies for folding RNA sequences into secondary structures including kissing hairpin motifs. The new idea is to construct a kissing hairpin...
137
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WABI
14 years 11 months ago
2010 Springer
Abstract. Haplotype Inference (HI) is a computational challenge of crucial importance in a range of genetic studies, such as functional genomics, pharmacogenetics and population ge...
135
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WABI
14 years 11 months ago
2010 Springer
In this paper we present a novel expectation-maximization algorithm for inference of alternative splicing isoform frequencies from high-throughput transcriptome sequencing (RNA-Seq...
119
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WABI
14 years 11 months ago
2010 Springer
Abstract. Applied Biosystems’ SOLiD system offers a low-cost alternative to the traditional Sanger method of DNA sequencing. We introduce two main algorithms of mapping SOLiD’...
122
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WABI
14 years 11 months ago
2010 Springer
Abstract. Genome sequencing will soon produce haplotype data for individuals. For pedigrees of related individuals, sequencing appears to be an attractive alternative to genotyping...
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