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BMCBI
2007
233views more  BMCBI 2007»
15 years 4 months ago
160-fold acceleration of the Smith-Waterman algorithm using a field programmable gate array (FPGA)
Background: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching s...
Isaac T. S. Li, Warren Shum, Kevin Truong
ALMOB
2006
110views more  ALMOB 2006»
15 years 4 months ago
Computing distribution of scale independent motifs in biological sequences
The use of Chaos Game Representation (CGR) or its generalization, Universal Sequence Maps (USM), to describe the distribution of biological sequences has been found objectionable ...
Jonas S. Almeida, Susana Vinga
ENVSOFT
2008
106views more  ENVSOFT 2008»
15 years 4 months ago
Analysis of self-describing gridded geoscience data with netCDF Operators (NCO)
1 The netCDF Operator (NCO) software facilitates manipulation and analysis of gridded2 geoscience data stored in the self-describing netCDF format. NCO is optimized to efficiently3...
Charles S. Zender
BMCBI
2006
122views more  BMCBI 2006»
15 years 4 months ago
A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks
Background:Receptors and scaffold proteins possess a number of distinct domains and bind multiple partners. A common problem in modeling signaling systems arises from a combinator...
Holger Conzelmann, Julio Saez-Rodriguez, Thomas Sa...
BMCBI
2006
153views more  BMCBI 2006»
15 years 4 months ago
2DDB - a bioinformatics solution for analysis of quantitative proteomics data
Background: We present 2DDB, a bioinformatics solution for storage, integration and analysis of quantitative proteomics data. As the data complexity and the rate with which it is ...
Lars Malmström, György Marko-Varga, Guni...