Background: Microarrays were first developed to assess gene expression but are now also used to map protein-binding sites and to assess allelic variation between individuals. Rega...
Richard P. Auburn, Roslin R. Russell, Bettina Fisc...
Background: Through the use of DNA microarrays it is now possible to obtain quantitative measurements of the expression of thousands of genes from a biological sample. This techno...
Background: Accurate methods for extraction of meaningful patterns in high dimensional data have become increasingly important with the recent generation of data types containing ...
Brandon W. Higgs, Jennifer W. Weller, Jeffrey L. S...
Background: Serial Analysis of Gene Expressions (SAGE) produces gene expression measurements on a discrete scale, due to the finite number of molecules in the sample. This means t...
Background: Non-coding RNAs (ncRNAs) have a multitude of roles in the cell, many of which remain to be discovered. However, it is difficult to detect novel ncRNAs in biochemical s...
Andrew V. Uzilov, Joshua M. Keegan, David H. Mathe...