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IPPS
2007
IEEE
15 years 3 months ago
Reconfigurable Architecture for Biological Sequence Comparison in Reduced Memory Space
DNA sequence alignment is a very important problem in bioinformatics. The algorithm proposed by Smith-Waterman (SW) is an exact method that obtains optimal local alignments in qua...
Azzedine Boukerche, Jan Mendonca Correa, Alba Cris...
DNA
2004
Springer
165views Bioinformatics» more  DNA 2004»
15 years 2 months ago
Computing by Observing Bio-systems: The Case of Sticker Systems
Abstract. A very common approach in chemistry and biology is to observe the progress of an experiment, and take the result of this observation as the final output. Inspired by thi...
Artiom Alhazov, Matteo Cavaliere
RECOMB
2002
Springer
15 years 9 months ago
A bayesian approach to transcript estimation from gene array data: the BEAM technique
We present a new statistically optimal approach to estimate transcript levels and ratios from one or more gene array experiments. The Bayesian Estimation of Array Measurements (BE...
Ron O. Dror, Jonathan G. Murnick, Nicola A. Rinald...
RECOMB
2009
Springer
15 years 10 months ago
A Robust Bayesian Two-Sample Test for Detecting Intervals of Differential Gene Expression in Microarray Time Series
Abstract. Understanding the regulatory mechanisms that are responsible for an organism's response to environmental changes is an important question in molecular biology. A fir...
Oliver Stegle, Katherine J. Denby, David L. Wild, ...
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WABI
2007
Springer
109views Bioinformatics» more  WABI 2007»
15 years 3 months ago
A Novel Method for Signal Transduction Network Inference from Indirect Experimental Evidence
In this paper we introduce a new method of combined synthesis and inference of biological signal transduction networks. A main idea of our method lies in representing observed cau...
Réka Albert, Bhaskar DasGupta, Riccardo Don...