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160
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BMCBI
2007
159views more  BMCBI 2007»
15 years 3 months ago
Computational genes: a tool for molecular diagnosis and therapy of aberrant mutational phenotype
Background: A finite state machine manipulating information-carrying DNA strands can be used to perform autonomous molecular-scale computations at the cellular level. Results: We ...
Israel Mark Martínez-Pérez, Gong Zha...
144
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IJDMB
2011
129views more  IJDMB 2011»
14 years 7 months ago
Modelling gene and protein regulatory networks with Answer Set Programming
: Recently, many approaches to model regulatory networks have been proposed in the systems biology domain, however the task is far from being solved. In this paper we propose an an...
Timur Fayruzov, Jeroen Janssen, Dirk Vermeir, Chri...
133
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CHI
2006
ACM
16 years 4 months ago
Getting a grip on tangible interaction: a framework on physical space and social interaction
Our current understanding of human interaction with hybrid or augmented environments is very limited. Here we focus on `tangible interaction', denoting systems that rely on e...
Eva Hornecker, Jacob Buur
121
Voted
BIRD
2008
Springer
109views Bioinformatics» more  BIRD 2008»
15 years 5 months ago
A Robust Class of Stable Proteins in the 2D HPC Model
The inverse protein folding problem is that of designing an amino acid sequence which has a prescribed native protein fold. This problem arises in drug design where a particular st...
Alireza Hadj Khodabakhshi, Ján Manuch, Aras...
128
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BMCBI
2010
116views more  BMCBI 2010»
15 years 3 months ago
A hybrid approach to protein folding problem integrating constraint programming with local search
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
Abu Zafer M. Dayem Ullah, Kathleen Steinhöfel