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BMCBI
2005
302views more  BMCBI 2005»
14 years 11 months ago
CGHPRO - A comprehensive data analysis tool for array CGH
Background: Array CGH (Comparative Genomic Hybridisation) is a molecular cytogenetic technique for the genome wide detection of chromosomal imbalances. It is based on the cohybrid...
Wei Chen, Fikret Erdogan, H.-Hilger Ropers, Steffe...
BMCBI
2005
109views more  BMCBI 2005»
14 years 11 months ago
Genome comparison without alignment using shortest unique substrings
Background: Sequence comparison by alignment is a fundamental tool of molecular biology. In this paper we show how a number of sequence comparison tasks, including the detection o...
Bernhard Haubold, Nora Pierstorff, Friedrich M&oum...
BMCBI
2005
117views more  BMCBI 2005»
14 years 11 months ago
An SVM-based system for predicting protein subnuclear localizations
Background: The large gap between the number of protein sequences in databases and the number of functionally characterized proteins calls for the development of a fast computatio...
Zhengdeng Lei, Yang Dai
BMCBI
2005
147views more  BMCBI 2005»
14 years 11 months ago
Calibration of mass spectrometric peptide mass fingerprint data without specific external or internal calibrants
Background: Peptide Mass Fingerprinting (PMF) is a widely used mass spectrometry (MS) method of analysis of proteins and peptides. It relies on the comparison between experimental...
Witold E. Wolski, Maciej Lalowski, Peter Jungblut,...
JCC
2002
127views more  JCC 2002»
14 years 11 months ago
Effective Born radii in the generalized Born approximation: The importance of being perfect
: Generalized Born (GB) models provide, for many applications, an accurate and computationally facile estimate of the electrostatic contribution to aqueous solvation. The GB models...
Alexey Onufriev, David A. Case, Donald Bashford