NAR
2016
9 years 11 months ago
2016
Mitochondria are complex organelles that house essential pathways involved in energy metabolism, ion homeostasis, signalling and apoptosis. To understand mitochondrial pathways in...
NAR
2016
9 years 11 months ago
2016
More than 90% of common variants associated with complex traits do not affect proteins directly, but instead the circuits that control gene expression. This has increased the urge...
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NAR
2016
9 years 11 months ago
2016
Whole genome sequencing has become one of the routine methods in molecular epidemiological practice. In this study, we present BacWGSTdb (http: //bacdb.org/BacWGSTdb), a bacterial...
NAR
2016
9 years 11 months ago
2016
Accumulating evidence has demonstrated that rewiring of metabolism in cells is an important hallmark of cancer. The percentage of patients killed by metabolic disorder has been es...
NAR
2016
9 years 11 months ago
2016
Repetitive DNA, especially that due to transposable elements (TEs), makes up a large fraction of many genomes. Dfam is an open access database of families of repetitive DNA elemen...
NAR
2016
9 years 11 months ago
2016
We previously presented DriverDB, a database that incorporates ∼6000 cases of exome-seq data, in addition to annotation databases and published bioinformatics algorithms dedicat...
NAR
2016
9 years 11 months ago
2016
Protein kinases play a crucial role in cell signaling and are important drug targets in several therapeutic areas. The KLIFS database contains detailed structural kinase-ligand in...
NAR
2016
9 years 11 months ago
2016
Ensembl Genomes (http://www.ensemblgenomes. org) is an integrating resource for genome-scale data from non-vertebrate species, complementing the resources for vertebrate genomics ...
NAR
2016
9 years 11 months ago
2016
Intron positions upon the mRNA transcript are sometimes remarkably conserved even across distantly related eukaryotic species. This has made the comparison of intron–exon archit...