RECOMB
2006
Springer
14 years 4 months ago
2006
Springer
RECOMB
2006
Springer
14 years 4 months ago
2006
Springer
For as long as biologists have been computing alignments of sequences, the question of what values to use for scoring substitutions and gaps has persisted. While some choices for s...
RECOMB
2006
Springer
14 years 4 months ago
2006
Springer
The assignment of orthologous genes between a pair of genomes is a fundamental and challenging problem in comparative genomics, since many computational methods for solving various...
RECOMB
2006
Springer
14 years 4 months ago
2006
Springer
Abstract. Pharmacogenomics and clinical studies that measure the temporal expression levels of patients can identify important pathways and biomarkers that are activated during dis...
RECOMB
2006
Springer
14 years 4 months ago
2006
Springer
MicroRNAs (miRNAs) have recently been discovered as an important class of non-coding RNA genes that play a major role in regulating gene expression, providing a means to control th...
RECOMB
2006
Springer
14 years 4 months ago
2006
Springer
In this paper, we address the problem of discovering novel non-coding RNA (ncRNA) using primary sequence, and secondary structure conservation, focusing on ncRNA families with pseu...
RECOMB
2006
Springer
14 years 4 months ago
2006
Springer
In this paper, we present CONTRAlign, an extensible and fully automatic framework for parameter learning and protein pairwise sequence alignment using pair conditional random field...
RECOMB
2006
Springer
14 years 4 months ago
2006
Springer
We present a model for predicting HLA class I restricted CTL epitopes. In contrast to almost all other work in this area, we train a single model on epitopes from all HLA alleles a...
RECOMB
2006
Springer
14 years 4 months ago
2006
Springer
Abstract. We present a fast converging method for distance-based phylogenetic inference, which is novel in two respects. First, it is the only method (to our knowledge) to guarante...
RECOMB
2006
Springer
14 years 4 months ago
2006
Springer
Abstract. A probabilistic graphical model is developed in order to detect the dependent evolution between different sites in biological sequences. Given a multiple sequence alignme...