196
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BMCBI
2011
14 years 8 months ago
2011
Background: Current approaches for identifying transcriptional regulatory elements are mainly via the combination of two properties, the evolutionary conservation and the overrepr...
186
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BMCBI
2011
14 years 8 months ago
2011
Background: The ability to search for and precisely compare similar phenotypic appearances within and across species has vast potential in plant science and genetic research. The ...
186
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BMCBI
2011
14 years 8 months ago
2011
Background: The popularity of massively parallel exome and transcriptome sequencing projects demands new data mining tools with a comprehensive set of features to support a wide r...
211
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BMCBI
2011
14 years 8 months ago
2011
Background: Gene set analysis (GSA) has become a successful tool to interpret gene expression profiles in terms of biological functions, molecular pathways, or genomic locations. ...
186
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BMCBI
2011
14 years 8 months ago
2011
Background: Alternative splicing of pre-mature RNA is an important process eukaryotes utilize to increase their repertoire of different protein products. Several types of differen...
188
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BMCBI
2011
14 years 8 months ago
2011
Background: Genome-wide transcriptional profiling of patient blood samples offers a powerful tool to investigate underlying disease mechanisms and personalized treatment decisions...
180
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BMCBI
2011
14 years 8 months ago
2011
Background: Results of phylogenetic analysis are often visualized as phylogenetic trees. Such a tree can typically only include up to a few hundred sequences. When more than a few...
152
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BMCBI
2011
14 years 8 months ago
2011
Background: Flux coupling analysis (FCA) is a useful method for finding dependencies between fluxes of a metabolic network at steady-state. FCA classifies reactions into subsets (...
210
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BMCBI
2011
14 years 8 months ago
2011
Background: The ever increasing sizes of population genetic datasets pose great challenges for population structure analysis. The Tracy-Widom (TW) statistical test is widely used ...