194
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BMCBI
2011
14 years 8 months ago
2011
Background: Pairwise sequence alignment methods are widely used in biological research. The increasing number of sequences is perceived as one of the upcoming challenges for seque...
177
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BMCBI
2011
14 years 8 months ago
2011
Background: Combining multiple evidence-types from different information sources has the potential to reveal new relationships in biological systems. The integrated information ca...
163
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BMCBI
2011
14 years 8 months ago
2011
Background: Copy number aberrations (CNAs) are an important molecular signature in cancer initiation, development, and progression. However, these aberrations span a wide range of...
163
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BMCBI
2011
14 years 8 months ago
2011
Background: Classification and variable selection play an important role in knowledge discovery in highdimensional data. Although Support Vector Machine (SVM) algorithms are among...
179
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BMCBI
2011
14 years 8 months ago
2011
Background: Protein-protein interactions play a fundamental role in elucidating the molecular mechanisms of biomolecular function, signal transductions and metabolic pathways of l...
197
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BMCBI
2011
14 years 8 months ago
2011
Background: High-throughput functional genomics technologies generate large amount of data with hundreds or thousands of measurements per sample. The number of sample is usually m...
169
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BMCBI
2011
14 years 8 months ago
2011
Background: Diabetes like many diseases and biological processes is not mono-causal. On the one hand multifactorial studies with complex experimental design are required for its c...
146
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BMCBI
2011
14 years 8 months ago
2011
Background: Chromatin immunoprecipitation (ChIP), coupled with massively parallel short-read sequencing (seq) is used to probe chromatin dynamics. Although there are many algorith...